Regional Association Score for Genome-Wide Association Studies


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Documentation for package ‘RAS’ version 1.1.2

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RAS-package RAS: Regional Association Score for Genome-Wide Association Studies
bed_to_rasbin Convert a PLINK 1 .bed/.bim/.fam Fileset to .rasbin
compute_gwas_weights Per-SNP GWAS Effect Size Weights
compute_gwas_weights_fast Aliases Kept from the Development Versions
compute_gwas_weights_original Per-SNP GWAS Effect Size Weights (Pure-R, In-Memory)
compute_pgs_matrix Build the Per-Individual PGS Contribution Matrix
geno_to_rasbin Write a Genotype Matrix to the Chunked .rasbin Format
get_break_points Detect a Single Changepoint via Segmented Regression
get_local_maximum Find the Local Maximum Within a Window
plot.ras Plot a RAS Result Object
print.ras Print a RAS Result Object
RAS RAS: Regional Association Score for Genome-Wide Association Studies
ras RAS: Regional Association Score Analysis
ras-aliases Aliases Kept from the Development Versions
rasbin_header Read the .rasbin File Header
rasbin_read_chunk Read a Column Range from a .rasbin File
ras_box_calibrate Calibrate the Box-Scan Threshold on Null Profiles
ras_box_detect Detect Elevated Regions with the Box Scan
ras_box_stat Box-Scan Statistic for Every Window Start and Width
ras_detect First-Pass Changepoint Detection via Sliding Window
ras_detect_fast Aliases Kept from the Development Versions
ras_detect_original First-Pass Changepoint Detection (Pure-R)
ras_fast Aliases Kept from the Development Versions
ras_harmonize_sumstats Harmonise External GWAS Summary Statistics into RAS Weights
ras_liftover_sumstats LiftOver External Summary Statistics onto the Map's Build (Route B2)
ras_map_ids_to_rsid Rename a Local Genotype Map's Variants to rsIDs (Harmonisation Route B0)
ras_memory Estimate Memory Requirements and Check System Readiness
ras_original RAS Pipeline (Pure-R, In-Memory)
ras_read_variant_dictionary Read a Variant Dictionary for Summary-Statistics Harmonisation
ras_scan RAS Stage 1: Averaged Regional Association Profile
ras_scan_external RAS Scan with External Weights on All Samples
ras_scan_external_fast Aliases Kept from the Development Versions
ras_scan_external_original Summary-Informed RAS Scan on All Samples (In-Memory)
ras_scan_fast Aliases Kept from the Development Versions
ras_scan_original RAS Stage 1 Scan (Pure-R, In-Memory)
ras_sumstats_report Inspect an External-Summary Alignment Without Committing to It
ras_validate Second-Pass Changepoint Validation
ras_weights_from_sumstats Align External GWAS Summary Statistics to a Local Genotype Map
release_memory Release Memory Back to the OS
screen_forward_max_region Forward Scan of the RAS Profile
screen_forward_max_region_fast Aliases Kept from the Development Versions
screen_forward_max_region_original Forward Scan of the RAS Profile (Pure-R, In-Memory)
slope_test One-Tailed Slope Test Through the Origin