IsletCalc: Calculators for Insulin and Glucagon Release Indices

Facilitates the calculation of validated pancreatic islet hormone-release indices from fasting and oral glucose tolerance test (OGTT) measurements. Provides beta-cell insulin release indices (including HOMA-beta, corrected insulin response, Stumvoll first-phase index, BIGTT-AIR, and disposition indices) as described in Madsen (2024) <doi:10.1038/s42255-024-01140-6>, alongside alpha-cell glucagon release and glucagon resistance indices derived from the glucagon-suppression and liver-alpha-cell-axis literature. Enables reproducible assessment of beta-cell and alpha-cell function for metabolic and endocrine research.

Version: 0.0.1
Depends: R (≥ 3.5.0)
Suggests: knitr, rmarkdown, spelling, testthat (≥ 3.0.0)
Published: 2026-07-16
DOI: 10.32614/CRAN.package.IsletCalc
Author: Sufyan Suleman ORCID iD [aut, cre]
Maintainer: Sufyan Suleman <sufyansuleman at hotmail.com>
BugReports: https://github.com/sufyansuleman/IsletCalc/issues
License: MIT + file LICENSE
URL: https://github.com/sufyansuleman/IsletCalc, https://sufyansuleman.github.io/IsletCalc/
NeedsCompilation: no
Language: en-US
Citation: IsletCalc citation info
Materials: README, NEWS
CRAN checks: IsletCalc results

Documentation:

Reference manual: IsletCalc.html , IsletCalc.pdf
Vignettes: Get started with IsletCalc (source, R code)

Downloads:

Package source: IsletCalc_0.0.1.tar.gz
Windows binaries: r-devel: IsletCalc_0.0.1.zip, r-release: IsletCalc_0.0.1.zip, r-oldrel: IsletCalc_0.0.1.zip
macOS binaries: r-release (arm64): IsletCalc_0.0.1.tgz, r-oldrel (arm64): IsletCalc_0.0.1.tgz, r-release (x86_64): IsletCalc_0.0.1.tgz, r-oldrel (x86_64): IsletCalc_0.0.1.tgz

Linking:

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